蛋白激酶抑制剂

  • Inventors:
  • Assignees: 奥赖恩公司
  • Publication Date: June 27, 2017
  • Publication Number: CN-105073733-B

Abstract

公开了式(I)的化合物及其可药用盐,其中R1至R5、A、B、Z、Z1和Z2如权利要求中所定义。式(I)的化合物可用作FGFR抑制剂并可用于治疗其中需要抑制FGFR激酶的病症,例如癌症。

Claims

Description

Topics

    Download Full PDF Version (Non-Commercial Use)

    Patent Citations (6)

      Publication numberPublication dateAssigneeTitle
      CN-101558068-AOctober 14, 2009诺瓦提斯公司Phenylacetamides useful as protein kinase inhibitors
      CN-1852905-AOctober 25, 2006Osi制药公司N-substituted benzimidazolyl c-kit inhibitors
      WO-0100207-A1January 04, 2001Merck & Co., Inc.Src kinase inhibitor compounds
      WO-0100214-A1January 04, 2001Merck & Co., Inc.Composes inhibiteurs de la kinase src
      WO-2008078100-A2July 03, 2008Astex Therapeutics LimitedTricyclic amine derivatives as protein tyrosine kinase inhibitors
      WO-2010119284-A1October 21, 2010Astex Therapeutics LimitedBicyclic heterocyclyl derivatives as fgfr kinase inhibitors for therapeutic use

    NO-Patent Citations (0)

      Title

    Cited By (0)

      Publication numberPublication dateAssigneeTitle